Dispositional pessimism and amygdala activity: a PET study in healthy volunteers
Dispositional pessimism and amygdala activity: a PET study in healthy volunteers
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DOI：
10.1097/00001756-200106130-00024
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发表时间：
2001-06-13
期刊：
影响因子：
1.7
通讯作者：
Fredrikson, M
中科院分区：
文献类型：
--
作者：
Fischer, H;Tillfors, M;Fredrikson, M
本研究使用塞利格曼的归因方式问卷得分和[O-15]水正电子发射断层扫描局部脑血流量(RCBF)测量来探讨性格悲观的个体差异与杏仁核活动的关系。在扫描过程中，13名没有蛇恐惧症的健康女性被动地观看了一盘蛇的录像带。采用单尾检验，悲观性得分与右侧(r=-0.6；p=0.014)和左侧杏仁核局部脑血流量(r=-0.53；p=0.032)之间存在显著的负相关。这些结果扩展了健康受试者之前的神经成像发现，表明杏仁核在短暂的负面情绪状态中发挥了作用，并表明这个多模式大脑区域也参与了更持久的负面影响，如性格悲观。《神经报告》12：1635-1638(C)2001 Lippincott Williams&Wilkins.
The present study used scores from Seligman's Attribution Style Questionnaire and [O-15] water positron emission tomographic measurements of regional cerebral blood flow (rCBF) to investigate the relation between individual differences in dispositional pessimism and amygdala activity. During scanning 13 healthy non-snake-phobic females passively viewed a snake videotape. Using one-tailed tests, significant negative correlations were evident between pessimism scores, with low scores reflecting relatively more pessimism, and right (r=-0.60; p=0.014) and left amygdala rCBF (r=-0.53;p=0.032). These results extend previous neuroimaging findings in healthy subjects indicating a role for the amygdala in transient negative emotional states, and suggest that this multimodal brain region also is involved in more durable negative affects such as dispositional pessimism. NeuroReport 12:1635-1638 (C) 2001 Lippincott Williams & Wilkins.