Amitriptyline, Weight Gain and Carbohydrate Craving: A Side Effect
Amitriptyline, Weight Gain and Carbohydrate Craving: A Side Effect
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阿米替林、体重增加和对碳水化合物的渴望：副作用
DOI：
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发表时间：
1973
影响因子：
10.5
通讯作者：
P. M. De la Vergne
中科院分区：
文献类型：
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作者：
E. Paykel;P. Mueller;P. M. De la Vergne
体重增加是吩噻嗪类药物的一种众所周知的副作用（Dally，1967）。有关于三环类抗抑郁药导致体重增加的零星报道（Arenillas，1964; Dally，1967; Kline，1969），但这种可能性几乎没有得到系统的研究。调查被抑郁本身经常导致体重减轻的事实所混淆。Crammer和Elkes（1968）报告了地昔帕明反应者的体重增加，但认为这是一种有限的现象，不会导致肥胖，而是由于抑郁症引起的体重减轻的逆转。
Increase in weight is a well-known side effect of phenothiazine drugs (Dally, 1967). There have been scattered reports of weight gain on tricyclic antidepressants (Arenillas, 1964; Dally, 1967; Kline, 1969), but this possibility has received little systematic study. Investigation is confounded by the fact that depression itself often produces weight loss. Crammer and Elkes (1968) reported weight gain in responders to desipramine, but regarded this as a limited phenomenon which never built up to obesity and was due to reversal of depression-induced weight loss.