A whole foxtail millet diet reduces blood pressure in subjects with mild hypertension
A whole foxtail millet diet reduces blood pressure in subjects with mild hypertension
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DOI：
10.1016/j.jcs.2018.09.003
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发表时间：
2018-11-01
影响因子：
3.8
通讯作者：
Shen, Qun
中科院分区：
文献类型：
--
作者：
Hou, Dianzhi;Chen, Jing;Shen, Qun
研究了谷子潜在的降压作用。参与者被招募参加为期12周的开放标签和自我对照试验，考虑整个谷子产品的外观和风味。筛选后，45名未接受治疗的轻度高血压患者平均每天食用约50克全谷子，代替部分常规主食进行临床干预，并纳入分析。测量包括血压、肾素血管紧张素醛固酮系统、血脂、空腹血糖、人体测量指数、身体成分和骨密度。在全谷子饮食干预12周后，观察到参与者的收缩压（4.13 mmHg, P = 0.022）和舒张压（3.49 mmHg, P = 0.002）显著降低。体质量指数、体脂率、脂肪质量显著降低（p < 0.05）。全谷子的摄入也改善了受试者的空腹血糖（p = 0.051）。全谷子作为一种潜在的营养品和功能性食品，具有改善高血压和减轻心血管疾病的作用。
The potential anti-hypertensive effect of foxtail millet was investigated. Participants were recruited to a 12 wk open-label and self-controlled trial, considering the appearance and flavor of whole foxtail millet products. After screening, 45 subjects with untreated mild hypertension received a daily average of approximately 50 g of whole foxtail millet, replacing their partial regular staple food for the clinical intervention, and were included in the analyses. Measurements included blood pressure, renin angiotensin aldosterone system, blood lipids, fasting blood glucose, anthropometric indices, body composition and bone density. After 12 wk of whole foxtail millet diet intervention, significant reductions in the participants' SBP (4.13 mmHg, P = 0.022) and DBP (3.49 mmHg, P = 0.002) were observed. In addition, the body mass index, body fat percentage, and fat mass significantly decreased (p < 0.05). The intake of whole foxtail millet also improved the subjects' fasting blood glucose (p = 0.051). Whole foxtail millet, which serves as a potential source of nutraceutical and functional food, may ameliorate hypertension and alleviate related cardiovascular diseases.