Type 1 interferons as a potential treatment against COVID-19
Type 1 interferons as a potential treatment against COVID-19
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DOI：
10.1016/j.antiviral.2020.104791
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发表时间：
2020-06-01
影响因子：
7.6
通讯作者：
Peiffer-Smadja, Nathan
中科院分区：
文献类型：
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作者：
Sallard, Erwan;Lescure, Francois-Xavier;Peiffer-Smadja, Nathan
1型干扰素在体外具有广泛的抗病毒活性，目前正在一项治疗中东呼吸综合征冠状病毒的临床试验中进行评估。在这篇综述中，我们讨论了1型干扰素对SARS-CoV-2的潜在活性的初步数据，以及在临床试验中评估这些分子治疗COVID-19的相关性。
Type 1 interferons have a broad antiviral activity in vitro and are currently evaluated in a clinical trial to treat MERS-CoV. In this review, we discuss preliminary data concerning the potential activity of type 1 interferons on SARS-CoV-2, and the relevance of evaluating these molecules in clinical trials for the treatment of COVID-19.