Prevalence of diabetes and impaired fasting glucose in adults in the US population - National Health and Nutrition Examination Survey 1999-2002

Prevalence of diabetes and impaired fasting glucose in adults in the US population - National Health and Nutrition Examination Survey 1999-2002
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DOI:
10.2337/dc06-0062
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发表时间:
2006-06-01
期刊:
影响因子:
16.2
通讯作者:
Gregg, Edward W.
Gregg, Edward W.
中科院分区:
医学1区
文献类型:
--
作者:
Cowie, Catherine C.;Engelgau, Michael M.;Gregg, Edward W.

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目的 - 这项研究的目的是检查1999年至2002年美国成年人的禁食糖尿病和未诊断糖尿病的患病率,并在1988年至1994年的美国成年人中损害了禁食葡萄糖(IFG)。健康和营养检查调查(NHANES)包含一个年龄> = 20岁的成年人的概率样本。在1999年至2002年的NHANES中,使用标准标准对4,761名成年人进行了血糖状态分类,该标准是基于诊断为糖尿病的访谈和在子样本中测得的禁食等离子体葡萄糖。 1930万,2002年美国人口),诊断为6.5%,未诊断2.8%。另外26.0%的IFG为糖尿病或IFG总计35.3%(7330万)。总糖尿病的患病率随着年龄的增长而增加,年龄> = 65岁的人达到21.6%。与非西班牙裔白人相比,非西班牙裔黑人和墨西哥裔美国人的诊断糖尿病患病率是高的两倍(P <0.00001),而未诊断的糖尿病的患病率则被种族/民族相似,对年龄和性别进行了调整。性别的诊断糖尿病患病率相似,但男性未诊断的糖尿病和IFG的患病率显着更高。诊断糖尿病的原状患病率从1988 - 1994年的5.1%显着上升到1999 - 2002年的6.5%,但对于未诊断的糖尿病(2.7%至2.8%)和LFG(从24.7%到24.7%到26,0%),原始患病率稳定。 。调整年龄和性别后的结果相似。结论 - 尽管诊断糖尿病的患病率在过去十年中显着增加,但未诊断的糖尿病和IFG的患病率仍然相对稳定。少数群体仍然受到不成比例的影响。
OBJECTIVE- The purpose of this study was to examine the prevalences of diagnosed and undiagnosed diabetes, and impaired fasting glucose (IFG) in U.S. adults during 1999-2002, and compare prevalences to those in 1988-1994.RESEARCH DESIGN AND METHODS- The National Health and Nutrition Examination Survey (NHANES) contains a probability sample of adults aged >= 20 years. In the NHANES 1999-2002, 4,761 adults were classified on glycemic status using standard criteria, based on an interview for diagnosed diabetes and fasting plasma glucose measured in a subsample.RESULTS- The crude prevalence of total diabetes in 1999-2002 was 9.3% (19.3 million, 2002 U.S. population), consisting of 6.5% diagnosed and 2.8% undiagnosed. An additional 26.0% had IFG, totaling 35.3% (73.3 million) with either diabetes or IFG. The prevalence Of total diabetes rose with age, reaching 21.6% for those aged >= 65 years. The prevalence of diagnosed diabetes was twice as high in non-Hispanic blacks and Mexican Americans compared with non-Hispanic whites (both P < 0.00001), whereas the prevalence of undiagnosed diabetes was similar by race/ethnicity, adjusted for age and sex. The prevalence of diagnosed diabetes was similar by sex, but prevalences of undiagnosed diabetes and IFG were significantly higher in men. The crude prevalence of diagnosed diabetes rose significantly from 5.1% in 1988-1994 to 6.5% in 1999-2002, but the crude prevalences were stable for undiagnosed diabetes (from 2.7 to 2.8%) and lFG (from 24.7 to 26,0%). Results were similar after adjustment for age and sex.CONCLUSIONS- Although the prevalence of diagnosed diabetes has increased significantly over the last decade, the prevalences of undiagnosed diabetes and IFG have remained relatively stable. Minority groups remain disproportionately affected.