Observation of a 1H double quantum filtered signal of water in biological tissues

Observation of a 1H double quantum filtered signal of water in biological tissues
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生物组织中水的 1H 双量子滤波信号的观察

DOI:
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发表时间:
1998
影响因子:
3.3
通讯作者:
G. Navon
G. Navon
中科院分区:
医学3区
文献类型:
--
作者:
L. Tsoref;H. Shinar;G. Navon

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据报道,在牛坐骨神经、牛关节软骨、大鼠尾腱和大鼠大脑中观察到水的 1H 双量子过滤 (DQF) NMR 信号。发现大鼠尾腱中该信号的起源是水质子和大分子质子之间残余偶极相互作用的结果。 1H DQF 光谱的宽度对方向的依赖性表明,在大鼠尾腱中,残余偶极相互作用的有效导向器平行于胶原纤维。 1H DQF NMR 可应用于成像,其中获得的对比度与组织的有序程度相关。
The observation of a 1H double quantum filtered (DQF) NMR signal of water in bovine sciatic nerve, bovine articular cartilage, rat tail tendon, and rat brain is reported. The origin of this signal in rat tail tendon was found to be a result of residual dipolar interaction between water protons and macromolecular protons. The dependence of the width of the 1H DQF spectra on the orientation indicated that in rat tail tendon the effective director of the residual dipolar interaction is parallel to the collagen fibers. 1H DQF NMR may be applied in imaging where the contrast obtained is related to the degree of order in the tissue.
DOI: 10.1126/science.8266096
发表时间: 1993-12-24
期刊: SCIENCE
影响因子: 56.9
作者:
WARREN, WS;RICHTER, W;FARMER, BT
通讯作者: FARMER, BT