Escherichia coli O104:H4 infections and international travel.
Escherichia coli O104:H4 infections and international travel.
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DOI：
10.3201/eid1803.111281
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发表时间：
2012-03
影响因子：
11.8
通讯作者：
Allen VG
中科院分区：
文献类型：
--
作者：
Alexander DC;Hao W;Gilmour MW;Zittermann S;Sarabia A;Melano RG;Peralta A;Lombos M;Warren K;Amatnieks Y;Virey E;Ma JH;Jamieson FB;Low DE;Allen VG
我们通过基因组测序和光学图谱分析了与旅行相关的大肠杆菌 O104:H4 临床分离株，其中 1 株来自 2011 年德国疫情爆发，1 株来自 2010 年从菲律宾返回的患者。尽管这些菌株之间的基因组具有广泛的相似性，但主要差异包括毒素的分布和抗菌药物耐药性决定因素。
We analyzed travel-associated clinical isolates of Escherichia coli O104:H4, including 1 from the 2011 German outbreak and 1 from a patient who returned from the Philippines in 2010, by genome sequencing and optical mapping. Despite extensive genomic similarity between these strains, key differences included the distribution of toxin and antimicrobial drug–resistance determinants.