Association between placental growth factor levels in early onset preeclampsia with the occurrence of postpartum hemorrhage: A prospective cohort study
Association between placental growth factor levels in early onset preeclampsia with the occurrence of postpartum hemorrhage: A prospective cohort study
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DOI：
10.1016/j.preghy.2011.11.006
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发表时间：
2012-04-01
影响因子：
2.2
通讯作者：
Agarwal, Sneh
中科院分区：
文献类型：
--
作者：
Ghosh, Sanjib Kumar;Raheja, Shashi;Agarwal, Sneh
目的：为了确定PlGF与（胎盘生长因子）估计中孕早期（孕22-24周），发生产后出血的孕妇是否与早发性子痫前期及分娩方式有关（剖宫产或阴道）与产后出血风险增加有任何关联。研究设计：对2009年3月至2011年6月期间诊断为早发性先兆子痫的788例单胎妊娠孕妇进行了前瞻性队列研究。母体血清PlGF水平估计在妊娠22至24周之间进行，并且截止值为
Objectives: To determine the association between PlGF (placental growth factor) estimation in early second trimester (22-24 weeks of gestation), with the occurrence of postpartum hemorrhage in pregnant women with early onset preeclampsia and whether the mode of delivery (cesarean or vaginal) has any association with increased risk of developing postpartum hemorrhage.Study design: A prospective cohort study was conducted on 788 pregnant women with singleton pregnancies diagnosed with early onset preeclampsia between March 2009 and June 2011. Maternal serum PlGF level estimation was done between 22 and 24 weeks of gestation and a cut-off value of