Identification of a novel coronavirus in bats
Identification of a novel coronavirus in bats
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DOI：
10.1128/jvi.79.4.2001-2009.2005
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发表时间：
2005-02-01
影响因子：
5.4
通讯作者：
Peiris, JSM
中科院分区：
文献类型：
--
作者：
Poon, LLM;Chu, DKW;Peiris, JSM
外来野生动物可以作为该地区地方性疾病的宿主，也可以通过种间传播成为新出现疾病的来源。最近出现的严重急性呼吸综合征相关冠状病毒（SARS-CoV）凸显了对野生动物进行病毒监测的重要性。在这里，我们报告通过对野生动物冠状病毒的监测发现了一种新的蝙蝠冠状病毒。ORF1b和s基因区RNA序列分析表明该病毒为1组冠状病毒。在三种蝙蝠（小翅蝠属）的粪便和呼吸道样本中检测到该病毒。特别是，63%（19份粪便样本中有12份）的pusillus粪便样本呈病毒阳性。这些发现表明，该病毒可能在香港的pusillus中普遍传播。
Exotic wildlife can act as reservoirs of diseases that are endemic in the area or can be the source of new emerging diseases through interspecies transmission. The recent emergence of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) highlights the importance of virus surveillance in wild animals. Here, we report the identification of a novel bat coronavirus through surveillance of coronaviruses in wildlife. Analyses of the RNA sequence from the ORF1b and S-gene regions indicated that the virus is a group 1 coronavirus. The virus was detected in fecal and respiratory samples from three bat species (Miniopterus spp.). In particular, 63% (12 of 19) of fecal samples from Miniopterus pusillus were positive for the virus. These findings suggest that this virus might be commonly circulating in M. pusillus in Hong Kong.