Positron detection in silica monoliths for miniaturised quality control of PET radiotracers.

Positron detection in silica monoliths for miniaturised quality control of PET radiotracers.
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DOI:
10.1039/c6cc00660d
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发表时间:
2016-05
影响因子:
4.9
通讯作者:
M. Tarn;D. Maneuski;Richard Alexander;N. J. Brown;V. O’Shea;S. Pimlott;N. Pamme;S. Archibald
M. Tarn;D. Maneuski;Richard Alexander;N. J. Brown;V. O’Shea;S. Pimlott;N. Pamme;S. Archibald
中科院分区:
化学2区
文献类型:
--
作者:
M. Tarn;D. Maneuski;Richard Alexander;N. J. Brown;V. O’Shea;S. Pimlott;N. Pamme;S. Archibald

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We demonstrate the use of the miniaturised Medipix positron sensor for detection of the clinical PET radiotracer, [(68)Ga]gallium-citrate, on a silica-based monolith, towards microfluidic quality control. The system achieved a far superior signal-to-noise ratio compared to conventional sodium iodide-based radio-HPLC detection and allowed real-time visualisation of positrons in the monolith.