Chromosome-Mediated Multidrug Resistance in Salmonella enterica Serovar Typhi
Chromosome-Mediated Multidrug Resistance in Salmonella enterica Serovar Typhi
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DOI：
10.1128/aac.04081-14
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发表时间：
2015-01-01
影响因子：
4.9
通讯作者：
Wang, Pei-Jen
中科院分区：
文献类型：
--
作者：
Chiou, Chien-Shun;Alam, Munirul;Wang, Pei-Jen
在来自孟加拉国的26株多重耐药肠道沙门氏菌伤寒血清型分离株中，有18株发现了一个沙门氏菌基因组岛，命名为SGI11。SGI 11是一个IS1复合转座子，携带7个抗性基因，对5种一线抗菌药物具有抗性。18架携带SGI 11的S.伤寒菌株对高浓度的环丙沙星产生了耐药性。
A salmonella genomic island, designated SGI11, was found in 18 of 26 multidrug-resistant Salmonella enterica serovar Typhi isolates from Bangladesh. SGI11 was an IS1 composite transposon and carried 7 resistance genes that conferred resistance to 5 first-line antimicrobials. Eleven of the 18 SGI11-carrying S. Typhi isolates had developed resistance to high levels of ciprofloxacin.