Two decades after vaccine license: Hepatitis B immunization and infection among young men who have sex with men
Two decades after vaccine license: Hepatitis B immunization and infection among young men who have sex with men
复制标题
DOI：
10.2105/ajph.91.6.965
复制
发表时间：
2001-06-01
影响因子：
12.7
通讯作者：
Janssen, RS
中科院分区：
文献类型：
--
作者：
MacKellar, DA;Valleroy, LA;Janssen, RS
目标。本研究调查了男男性行为者 (MSM) 中的乙型肝炎免疫覆盖率和乙型肝炎病毒 (HBV) 感染程度，自 1982 年以来就建议对该群体接种乙型肝炎疫苗。方法。我们分析了 1994 年至 1998 年间在美国 7 个大都市区 194 个同性恋识别场所随机抽取的 3432 名 15 至 22 岁 MSM 的数据。参与者接受了访谈咨询，并检测了 HBV 感染的血清学标志物。结果。免疫覆盖率为 9%，乙型肝炎病毒感染标志物患病率为 11%。 15 岁人群中乙肝病毒感染率为 2%，22 岁人群中乙肝病毒感染率为 17%。在易感染 HBV 的参与者中，96% 使用常规医疗保健来源或访问医疗保健系统进行 HIV 或性传播疾病检测。结论。尽管有效疫苗的问世已近 20 年，但我们的研究结果表明，在美国，很少有青少年和年轻的 MSM 接种了乙型肝炎疫苗。医疗保健提供者应加大努力，识别易感染 HBV 的年轻 MSM 并为其接种疫苗。
Objectives. This study investigated hepatitis B immunization coverage and the extent of hepatitis B virus (HBV) infection among young men who have sex with men (MSM), a group for whom hepatitis B vaccine has been recommended since 1982.Methods. We analyzed data from 3432 MSM, aged 15 to 22 years, randomly sampled at 194 gay-identified venues in 7 US metropolitan areas from 1994 through 1998. Participants were interviewed counseled, and tested for serologic markers of HBV infection.Results. Immunization coverage was 9% and the prevalence of markers of HBV infection was 11%. HBV infection ranged from 2% among 15-year-olds to 17% among 22-year-olds. Among participants susceptible to HBV infection, 96% used a regular source of health care or accessed the health care system for HIV or sexually transmitted disease testing.Conclusions. Despite the availability of an effective vaccine for nearly 2 decades, our findings suggest that few adolescent and young adult MSM in the United States are vaccinated against hepatitis B. Health care providers should intensify their efforts to identify and vaccinate young MSM who are susceptible to HBV.