Congenital biliary dilatation in dizygotic twins
Congenital biliary dilatation in dizygotic twins
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DOI：
10.1007/s00383-004-1255-y
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发表时间：
2005-01-01
影响因子：
1.8
通讯作者：
Kamiyama, Y
中科院分区：
文献类型：
--
作者：
Tokuhara, K;Hamada, Y;Kamiyama, Y
摘要不同类型之先天性胆道扩张症是近年来在双卵双胞胎中发现的。我们的病例表明遗传性参与CBD的可能性。另一方面，CBD不一致的六套单卵双胞胎已被报道，这将表明CBD的发生是不兼容的单基因控制，虽然环境因素是合理的。为了评估可能与CBD有关的遗传因素，有必要积累更多的家族病例，并进一步研究遗传。
Congenital biliary dilatation (CBD) of different types was recently noted in dizygotic twins. Our cases suggest the possibility of hereditary involvement in CBD. On the other hand, CBD discordance in six sets of monozygotic twins has been reported, which would suggest that the occurrence of CBD is not compatible with single gene control, although environmental factors are plausible. To evaluate the genetic factors that may be implicated in CBD, it would be necessary to accumulate more familial cases and examine further studies on inheritance.