Characterization of di-, tri-, and tetranucleotide microsatellite markers with perfect repeats for Trypanosoma brucei and related species.

Characterization of di-, tri-, and tetranucleotide microsatellite markers with perfect repeats for Trypanosoma brucei and related species.
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DOI:
10.1111/j.1471-8286.2006.01297.x
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发表时间:
2006-06
期刊:
MOLECULAR ECOLOGY NOTES
影响因子:
--
通讯作者:
Caccone, Adalgisa
Caccone, Adalgisa
中科院分区:
其他
文献类型:
--
作者:
Balmer, Oliver;Palma, Christopher;Macleod, Annette;Caccone, Adalgisa

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Trypanosoma brucei, unicellular parasites causing human sleeping sickness and animal nagana, have a great impact on the socio-economic environment of sub-Saharan Africa. The dynamics of the parasite are still poorly understood. We have characterized 14 polymorphic di-, tri-, and tetranucleotide microsatellite loci with perfect repeats (only one motif) exhibiting between 5 and 16 alleles in T. brucei isolates from all over Africa and from all described subspecies. The microsatellites will be useful in addressing population genetic questions in T. brucei to better understand the population structure and spread of this important parasite.