Graphene quantum dots anchored onto mercaptopyridine-substituted zinc phthalocyanine-Au@Ag nanoparticle hybrid: Application as fluorescence "off-on-off" sensor for Hg2+ and biothiols
Graphene quantum dots anchored onto mercaptopyridine-substituted zinc phthalocyanine-Au@Ag nanoparticle hybrid: Application as fluorescence "off-on-off" sensor for Hg2+ and biothiols
复制标题
DOI：
10.1016/j.dyepig.2017.06.002
复制
发表时间：
2017-10-01
影响因子：
4.5
通讯作者：
Nyokong, Tebello
中科院分区：
文献类型：
--
作者：
Achadu, Ojodomo J.;Nyokong, Tebello
本文提出了一种新型的含聚乙烯亚胺官能化石墨烯量子点(PEIGQds)和硫代吡啶取代的锌(Pc)-Au@Ag纳米合金的超分子杂化材料。将所设计的杂化材料用作双荧光纳米探针，以PEI-GQds为荧光开关信号探针检测水溶液中的Hg2+和生物硫醇。分析物检测的双传感平台首先是基于Pc-Au@Ag共轭化合物与TC-n相互作用或静电吸引时PEIGQds荧光的猝灭(关闭)。在Hg2+存在的情况下，猝灭的荧光可以切换回“开”模式，当引入生物硫醇通过形成强的金属硫醇键(Hg-S)捕获Hg2+离子时，该荧光可以再次“关”。不同数量的Hg2+和生物硫醇对“关-开-关”过程进行了调节。在其他氨基酸和金属离子存在的情况下，纳米探针对目标分析物具有高度的稳定性和选择性。此外，该探针还成功地应用于添加样品中的测试分析物的分析。(C)2017爱思唯尔有限公司。保留所有权利。
Novel supramolecular hybrid containing polyethyleneimine-functionalized graphene quantum dots (PEIGQDs) and mercaptopyridine-substituted zinc phthalocyanine (Pc)-Au@Ag nano-alloys is presented in this study. The designed hybrid was employed as a dual fluorescence nanoprobe for Hg2+ and biothiol detection in aqueous solution using PEI-GQDs as the fluorescence switching signal probe. The dual sensing platform for the analytes detection is firstly, based on the quenching (turn "OFF") of the PEIGQDs fluorescence upon TC-n interaction or electrostatic attraction with Pc-Au@Ag conjugate. The quenched fluorescence can be switched back to the "ON" mode in the presence of Hg2+ and switched "OFF" again when biothiols are introduced to capture the Hg2+ ion via the formation of the strong metalthiol bond (Hg-S). The "off-on-off' processes were modulated by different amounts of Hg2+ and biothiols. The nanoprobes were found to be highly stable and selective towards the target analytes in the presence of other amino acids and metal ions. Also, the probes were successfully deployed in the assay of the test analytes in spiked samples. (C) 2017 Elsevier Ltd. All rights reserved.