Expression of taste signal transduction molecules in the caecum of common marmosets.
Expression of taste signal transduction molecules in the caecum of common marmosets.
复制标题
普通狨猴盲肠中味觉信号转导分子的表达。
DOI：
10.1098/rsbl.2013.0409
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发表时间：
2013
期刊：
影响因子：
3.3
通讯作者：
Imai H
中科院分区：
文献类型：
--
作者：
Gonda S;Matsumura S;Saito S;Go Y;Imai H
味觉信号转导蛋白的口外存在最近已被报道在啮齿动物和人类。在这里，我们报告的第一次，这些信号转导蛋白在盲肠的非人灵长类动物，常见的绒猴的存在。对普通绒猴味觉信号转导分子（gustducin和TRPM 5）基因表达的定量RT-PCR数据表明，在盲肠中有高表达，这在其他非人灵长类动物中没有观察到。免疫组织化学分析证实了特定的存在，在绒猴盲肠细胞的gustducin和味觉受体。这些结果可能与特定的取食行为的绒猴，消耗植物分泌物，主要是树胶。
The extraoral presence of taste signal transduction proteins has recently been reported in rodents and humans. Here, we report for the first time the presence of these signal transduction proteins in the caecum of a non-human primate, the common marmoset. Quantitative RT-PCR data on the gene expression of taste signal transduction molecules (gustducin and TRPM5) in common marmosets suggested high expression in the caecum, which was not observed in other non-human primates. Immunohistochemical analysis confirmed the specific presence of gustducin and taste receptors in marmoset caecal cells. These results may relate to the specific feeding behaviour of marmosets, which consume plant exudates, primarily gums.