Pseudosarcoma of the larynx: a comprehensive analysis.
Pseudosarcoma of the larynx: a comprehensive analysis.
复制标题
喉假性肉瘤：综合分析。
DOI：
10.1001/archotol.1980.00790350042012
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发表时间：
1980
影响因子：
--
通讯作者：
G. Berci
中科院分区：
文献类型：
--
作者：
P. Lambert;P. Ward;G. Berci
喉假肉瘤是一种罕见且有争议的恶性肿瘤。鳞状细胞癌与间变性梭形细胞间质相邻构成了该肿瘤独特的组织病理学表现。喉假肉瘤是最常见的息肉样声门肿块。这种病变的预后最好，而对无底瘤、声门上或下咽受累的预后较差。肿瘤表现出与喉部鳞状细胞癌相似的生物学行为，具有局部侵袭性和向局部淋巴和远处转移的能力。手术是治疗的选择，即使是T1声门病变，因为放射治疗与高局部复发率有关。
Pseudosarcoma of the larynx is a rare and controversial malignant neoplasm. The presence of a squamous cell carcinoma contiguous with an anaplastic-appearing spindle cell stroma constitutes the distinctive histopathologic appearance of this tumor. Laryngeal pseudosarcoma is most commonly seen as a polypoid glottic mass. Prognosis is best for this lesion and less favorable for sessile tumors and for supraglottic or hypopharyngeal involvement. The tumor demonstrates a biologic behavior similar to squamous cell carcinoma of the larynx, with local aggressiveness and metastatic capability to regional lymphatics and distant sites. Surgery is the treatment of choice, even for T1 glottic lesions, as radiation therapy is associated with a high local recurrence rate.