Asymmetric synthesis of α-chiral dihydrocinnamates by catalytic reductive aldol coupling and subsequent dehydroxylation
Asymmetric synthesis of α-chiral dihydrocinnamates by catalytic reductive aldol coupling and subsequent dehydroxylation
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DOI：
10.1016/j.tet.2007.10.055
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发表时间：
2007-12-24
期刊：
影响因子：
2.1
通讯作者：
Nishiyama, Hisao
中科院分区：
文献类型：
--
作者：
Hashimoto, Toru;Shiomi, Takushi;Nishiyama, Hisao
以取代肉桂酸酯和苯甲醛衍生物为原料，在Rh（Phebox）催化下，通过不对称还原Aldol偶联反应和脱羟基反应，合成了α位带有手性碳中心的光学活性二氢肉桂酸酯衍生物。(c)2007爱思唯尔有限公司保留所有权利。
Optically active dihydrocinnamate derivatives bearing the chiral carbon center at a-position were synthesized by Rh(Phebox)-catalyzed asymmetric reductive aldol coupling reaction with substituted cinnamates and benzaldehyde derivatives and subsequent dehydroxylation reaction. (c) 2007 Elsevier Ltd. All rights reserved.