Rational Fabrication of Anti-Freezing, Non-Drying Tough Organohydrogels by One-Pot Solvent Displacement
Rational Fabrication of Anti-Freezing, Non-Drying Tough Organohydrogels by One-Pot Solvent Displacement
复制标题
一锅溶剂置换法合理制备抗冻、不干燥的坚韧有机水凝胶
DOI：
10.1002/anie.201803366
复制
发表时间：
2018-05-28
影响因子：
16.6
通讯作者：
Zhou, Xuechang
中科院分区：
文献类型：
--
作者：
Chen, Fan;Zhou, Dan;Zhou, Xuechang
坚韧的水凝胶是具有优异机械性能（例如高拉伸性和韧性）的聚合物网络结构，是新兴的软材料。尽管具有显着的机械特性，坚韧的水凝胶仍存在两个缺陷（在水的结冰温度附近冻结和在干旱条件下干燥）。受用于抑制生物样品中水结冰的冷冻保护剂 (CPA) 的启发，据报道，一种通用且简单的方法可以通过部分置换预制水凝胶中的水分子来制造具有长期稳定性的极端抗冻、不干燥的基于 CPA 的有机水凝胶。用甘油、乙二醇和山梨醇成功制备了基于 CPA 的海藻酸钙/聚丙烯酰胺 (PAAm) 坚韧水凝胶。基于 CPA 的有机水凝胶即使在 -70 摄氏度以下也能保持不冻结和机械柔性，并且在环境条件甚至真空下保持稳定。
Tough hydrogels, polymeric network structures with excellent mechanical properties (such as high stretchability and toughness), are emerging soft materials. Despite their remarkably mechanical features, tough hydrogels exhibit two flaws (freezing around the icing temperatures of water and drying under arid conditions). Inspired by cryoprotectants (CPAs) used in the inhibition of the icing of water in biological samples, a versatile and straightforward method is reported to fabricate extreme anti-freezing, non-drying CPA-based organohydrogels with long-term stability by partially displacing water molecules within the pre-fabricated hydrogels. CPA-based Ca-alginate/polyacrylamide (PAAm) tough hydrogels were successfully fabricated with glycerol, glycol, and sorbitol. The CPA based organohydrogels remain unfrozen and mechanically flexible even up to -70 degrees C and are stable under ambient conditions or even vacuum.