Prospective study of Streptococcus milleri bacteremia
Prospective study of Streptococcus milleri bacteremia
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DOI：
10.1007/bf01591353
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发表时间：
1996-03-01
影响因子：
4.5
通讯作者：
Varela, J
中科院分区：
文献类型：
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作者：
Casariego, E;Rodriguez, A;Varela, J
在一项由米勒链球菌群微生物引起的菌血症的前瞻性研究中，在七年的时间内观察了总共 32 名成年患者。这些患者占研究期间诊断为严重菌血症的所有患者的 1.6%，占所有诊断的链球菌（非肺炎球菌）菌血症病例的 17%。只有 5 例患者患有多种微生物菌血症，在 31 例患者中，确定了推测的感染源，一般是口腔或胃肠道疾病，只有 6 例是院内获得的。最常见的症状是长时间发烧。记录了以下表现形式：菌血症伴局部化脓性感染（56%）、菌血症不伴局部化脓性感染（25%）和心内膜炎（19%）。 20 例（62%）在腹腔中发现相关感染灶，死亡率为 12.5%，所有分离株均对青霉素敏感，在解释米勒链球菌群有机体血培养阳性时必须小心，因为与其他草绿色链球菌不同，它们很少是污染物。因此，必须仔细检查患有化脓性过程和/或消化道疾病的患者。
In a prospective study of bacteremia caused by organisms of the Streptococcus milleri group a total of 32 adult patients were observed over a seven-year period. These patients accounted for 1.6% of all patients diagnosed as having significant bacteremia and 17% of all cases of streptococcal (nonpneumococcal) bacteremia diagnosed during the study period. Only five patients had polymicrobic bacteremia, In 31 cases, a presumed origin of infection was identified, generally oral or gastrointestinal disease, There were only six cases of nosocomial acquisition. The most common presenting symptom was prolonged fever. The following forms of presentation were documented: bacteremia with local suppurative infection (56%), bacteremia without local suppurative infection (25%), and endocarditis (19%). An associated focus of infection was found in the abdominal cavity in 20 cases (62%), The mortality rate was 12.5%, All isolates were susceptible to penicillin, Caution is necessary in interpreting a blood culture positive for Streptococcus milleri group organisms, since, unlike other viridans streptococci, they are rarely contaminants. For this reason patients with suppurative processes and/or digestive tract disease must be carefully investigated.