Videocapillaroscopic alterations in erythematotelangiectatic rosacea
Videocapillaroscopic alterations in erythematotelangiectatic rosacea
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DOI：
10.1016/j.jaad.2005.10.009
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发表时间：
2006-01-01
影响因子：
13.8
通讯作者：
Girolomoni, G
中科院分区：
文献类型：
--
作者：
Rosina, P;Zamperetti, MR;Girolomoni, G
背景：酒渣鼻是一种累及面部皮肤微血管的常见慢性皮肤病。有没有客观的措施来评估的严重程度approximatotelangiectatic酒渣鼻。Objective：我们的目的是表征和提供客观的措施血管的变化approximatotelangiectatic酒渣鼻videocapillaroscopy.Methods：我们比较了30例approximatotelangiectatic酒渣鼻与30名年龄和性别匹配的面部脂溢性皮炎患者和30名健康对照组。在脸颊和甲襞区域进行了视频毛细血管镜检查。面部的分析参数是形态学（背景颜色，血管不规则性）和定量（多边形净周长，毛细血管扩张，血管直径）。结果：面部酒渣鼻中观察到皮肤血管的特征性改变，与面部脂溢性皮炎的模式不同。特别是酒渣鼻显示新生血管和显着较大的多边形（13.21 +/- 3 vs 7.8 +/- 3 mm;平均值+/-标准差，P < .001），更显著的毛细血管扩张（267.8 +/- 108 vs 118.2 +/- 35 μ m; P < .001）和更大的平均血管直径（46.71 +/- 9 vs 24 +/- 10 μ m; P < .001）。脂溢性皮炎表现为多角形不规则和血管迂曲。相比之下，没有差异，发现在甲襞region.Limitations：血管不规则性和整体红斑可能难以quantified.Conclusions：视频毛细血管镜检查可能是一个有效的诊断方法，在早期诊断和测量毛细血管扩张性酒渣鼻。
Background: Rosacea is a common chronic dermatosis that involves the cutaneous microvasculature of the face. There are no objective measures for assessing the severity of erythematotelangiectatic rosacea.Objective: Our purpose was to characterize and provide objective measures of vessel changes in erythematotelangiectatic rosacea by videocapillaroscopy.Methods: We compared 30 patients with erythematotelangiectatic rosacea with 30 age- and sex-matched patients with facial seborrheic dermatitis and 30 healthy control subjects. Videocapillaroscopy was performed both on the cheeks and on the nailfold region. The analyzed parameters of the face were morphological (background color, vessel irregularities) and quantitative (polygonal net perimeter, telangiectasia, and vessel diameters).Results: Characteristic alterations of skin vessels were observed in facial rosacea, with a pattern distinct from that of facial seborrheic dermatitis. In particular, rosacea showed neoangiogenesis and significantly larger polygons (13.21 +/- 3 vs 7.8 +/- 3 mm; mean +/- standard deviation, P < .001), more prominent telangiectases (267.8 +/- 108 vs 118.2 +/- 35 mu m; P < .001) and larger mean vessel diameter (46.71 +/- 9 vs 24 +/- 10 mu m; P < .001) compared with seborrheic dermatitis. Seborrheic dermatitis displayed more polygon irregularities and vessel tortuosity. In contrast, no differences were found in the nailfold region.Limitations: Vessel irregularities and overall erythema may be difficult to quantify.Conclusions: Videocapillaroscopy may represent a valid adjunctive method in the early diagnosis and measurement of erythematotelangiectatic rosacea.