Three approaches for estimating the elastic modulus of the tympanic membrane
Three approaches for estimating the elastic modulus of the tympanic membrane
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DOI：
10.1016/j.jbiomech.2004.08.022
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发表时间：
2005-09-01
影响因子：
2.4
通讯作者：
Steele, C
中科院分区：
文献类型：
--
作者：
Fay, J;Puria, S;Steele, C
中耳的功能是解决耳道内空气与内耳液体之间的声阻抗不匹配问题。如果没有这种阻抗匹配，很少的声能被耳蜗吸收。这个过程的第一步是鼓膜（TM）将耳道中的声音转化为中耳骨的振动。了解TM如何在如此宽的频率范围内如此成功地管理其任务，将导致更令人满意和更少变化的TM修复（鼓膜成形术）。此外，了解TM的机制对于改善听骨假体与TM之间的耦合是必要的。数学模型在帮助研究界理解鼓膜的力学方面发挥了核心作用。然而，所有模型都需要参数作为输入。不幸的是，为TM建模所需的大多数参数都不是众所周知的。在这项工作中，探索了几种推断TM材料性质的方法。首先，利用本构模型根据胶原蛋白的弹性模量和实验观察到的纤维密度来估计弹性模量。其次，利用复合材料层压理论对文献中的拉伸和弯曲试验结果进行了重新解释。最后，将cat TM的动态测量与复合壳模型结合使用，以约束材料参数。从文献，测量和建模工作的值，以及从目前的分析汇集在一起，形成一个连贯的图像TM的材料特性。在人体中，数据将弹性模量限定在0.1到0.3 GPa之间。在cat中，数据显示的范围为0.1-0.4 GPa。这些数值明显高于以前的估计。(C) 2004 Elsevier Ltd.版权所有。
The function of the middle ear is to resolve the acoustic impedance mismatch between the air in the ear canal and the fluid of the inner ear. Without this impedance matching, very little acoustic energy would be absorbed into the cochlea. The first step in this process is the tympanic membrane (TM) converting sound in the ear canal into vibrations of the middle ear bones. Understanding how the TM manages its task so successfully over such a broad frequency range should lead to more satisfactory and less variable TM repairs (myringoplasty). In addition, understanding the mechanics of the TM is necessary to improve the coupling between ossicular prostheses and the TM. Mathematical models have played a central role in helping the research community understand the mechanics of the eardrum. However, all models require parameters as inputs. Unfortunately, most of the parameters needed for modeling the TM are not well known. In this work, several approaches for inferring the material properties of the TM are explored. First, constitutive modeling is used to estimate an elastic modulus based on the elastic modulus of collagen and experimentally observed fiber densities. Second, experimental tension and bending test results from the literature are re-interpreted using composite laminate theory. Lastly, dynamic measurements of the cat TM are used in conjunction with a composite shell model to bound the material parameters. Values from the literature, both measurement and modeling efforts, and from the present analysis are brought together to form a coherent picture of the TM's material properties. In the human, the data bound the elastic modulus between 0.1 and 0.3 GPa. In the cat, the data suggest a range of 0.1-0.4 GPa. These values are significantly higher than previous estimates. (C) 2004 Elsevier Ltd. All rights reserved.