Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2
Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2
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DOI：
10.1093/cid/ciaa848
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发表时间：
2021-03-15
影响因子：
11.8
通讯作者：
Mubareka, Samira
中科院分区：
文献类型：
--
作者：
Jamal, Alainna J.;Mozafarihashjin, Mohammad;Mubareka, Samira
我们在加拿大多伦多的6家医院招募了91名连续住院的COVID-19患者，并使用实时RT-PCR对每位患者的1个鼻咽拭子/唾液样本对进行了严重急性呼吸综合征冠状病毒2的检测。鼻咽拭子的敏感性为89%，唾液为72%（P = .02）。敏感性的差异是最大的样本对收集后，在疾病。
We enrolled 91 consecutive inpatients with COVID-19 at 6 hospitals in Toronto, Canada, and tested 1 nasopharyngeal swab/ saliva sample pair from each patient using real-time RT-PCR for severe acute respiratory syndrome coronavirus 2. Sensitivity was 89% for nasopharyngeal swabs and 72% for saliva (P = .02). Difference in sensitivity was greatest for sample pairs collected later in illness.