Importance of extracolonic findings at IV contrast medium-enhanced CT colonography versus those at non-enhanced CT colonography

Importance of extracolonic findings at IV contrast medium-enhanced CT colonography versus those at non-enhanced CT colonography
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DOI:
10.1007/s00330-005-2798-6
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发表时间:
2005-10-01
期刊:
影响因子:
5.9
通讯作者:
Hoppe, H
Hoppe, H
中科院分区:
医学2区
文献类型:
--
作者:
Spreng, A;Netzer, P;Hoppe, H

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比较静脉(IV)增强CT结肠镜与非增强CT结肠镜结肠外发现的临床重要性。对102例有症状的患者进行静脉造影剂中等增强(n=72)和非增强(n=30)多探测器CT结肠镜检查,并在同一天进行常规结肠镜检查。结肠外发现对进一步工作和治疗的影响是通过对患者记录的回顾来评估的。结肠外的发现分为两组:要么导致进一步的工作,分别对治疗有影响,要么没有。共检出303例结肠外病变。其中,71%(215/303)在IV增强CT上发现,29%(88/303)在非增强CT结肠镜上发现。25%(26/102)患者的结肠外发现导致进一步的工作或对治疗产生影响。其中22例患者接受了CT结肠镜造影并进行了静脉造影剂增强,4例未进行。结肠外发现导致进一步工作或对治疗产生影响的百分比,IV增强CT扫描(31%;22/72)高于非增强CT扫描(13%;4/30)(P=0.12)。对比增强CT结肠镜比非增强CT结肠镜产生更多的结肠外发现。与非增强CT结肠镜检查相比,IV增强CT结肠镜检查结果导致进一步工作和治疗的比例要大得多。
To compare the clinical importance of extracolonic findings at intravenous (IV) contrast-enhanced CT colonography versus those at non-enhanced CT colonography. IV contrast medium-enhanced (n=72) and non-enhanced (n=30) multidetector CT colonography was performed in 102 symptomatic patients followed by conventional colonoscopy on the same day. The impact of extracolonic findings on further work up and treatment was assessed by a review of patient records. Extracolonic findings were divided into two groups: either leading to further work up respectively having an impact on therapy or not. A total of 303 extracolonic findings were detected. Of those, 71% (215/303) were found on IV contrast-enhanced CT, and 29% (88/303) were found on non-enhanced CT colonography. The extracolonic findings in 25% (26/102) of all patients led to further work up or had an impact on therapy. Twenty-two of these patients underwent CT colonography with IV contrast enhancement, and four without. The percentage of extracolonic findings leading to further work up or having an impact on therapy was higher for IV contrast-enhanced (31%; 22/72) than for non-enhanced (13%; 4/30) CT scans (P=0.12). IV contrast-enhanced CT colonography produced more extracolonic findings than non-enhanced CT colonography. A substantially greater proportion of findings on IV contrast-enhanced CT colonography led to further work up and treatment than did non-enhanced CT colonography.