Labeling of calcitonin gene-related peptide and substance P increases in subnucleus caudalis of rabbit during maxillary sinusitis.
Labeling of calcitonin gene-related peptide and substance P increases in subnucleus caudalis of rabbit during maxillary sinusitis.
复制标题
上颌窦炎时兔尾亚核中降钙素基因相关肽和 P 物质的标记增加。
DOI：
10.1016/s0006-8993(97)01556-4
复制
发表时间：
1998
期刊：
影响因子：
2.9
通讯作者：
Kajander,KC
中科院分区：
文献类型：
--
作者：
Roche,AK;Koutlas,IG;Kajander,KC
采用免疫组织化学方法检测大鼠鼻窦炎模型后尾侧亚核内降钙素基因相关肽样免疫反应性（CGRP-LI）和P物质样免疫反应性（SP-LI）。诱导后3d，同侧尾侧亚核内CGRP-LI和SP-LI的标记强度增加。CGRP-LI和SP-LI的标记在随后的时间点（20和28天）显示正常。这些神经肽的早期变化可能有助于炎症过程和伴随鼻窦炎的疼痛症状。
Calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) and substance P-like immunoreactivity (SP-LI) were evaluated in subnucleus caudalis following induction of sinusitis. Three days after induction, intensity of labeling for CGRP-LI and SP-LI increased in ipsilateral subnucleus caudalis. Labeling for CGRP-LI and SP-LI appeared normal at later time points (20 and 28 days). Early changes in these neuropeptides may contribute to the inflammatory process and painful symptoms accompanying sinusitis.