Recurrent abdominal pain: a potential precursor of irritable bowel syndrome in adolescents and young adults.
Recurrent abdominal pain: a potential precursor of irritable bowel syndrome in adolescents and young adults.
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DOI：
10.1016/s0022-3476(98)70400-7
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发表时间：
1998-06
期刊：
影响因子：
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通讯作者：
L. Walker;Jessica W Guite;M. Duke;J. Barnard;J. Greene
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文献类型：
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作者：
L. Walker;Jessica W Guite;M. Duke;J. Barnard;J. Greene
目的评估复发性腹痛（RAP）患者在初次评估5年后的肠易激综合征（IBS）症状，确定IBS症状与功能障碍和卫生服务使用的关系，并确定在何种程度上IBS症状与生活压力和不良的心理社会adjustment.MethodsPatients RAP（n = 76）和对照组（n = 49）完成电话面试;测量包括肠道疾病问卷、功能障碍量表、生活事件问卷、家庭生活事件量表、流行病学研究中心抑郁量表、青少年自我感知概况和健康资源量表。RAP患者报告的腹痛发作次数明显多于对照组，功能障碍、缺课和因腹痛就诊的次数也明显高于对照组。RAP女性患者比女性对照组更可能符合IBS的曼宁标准。RAP患者中，更高水平的IBS症状与显着更大的功能障碍，更多的诊所访问，更多的生活压力，更高水平的抑郁症，和较低的学术和社会capability.ConclusionFemale患者与RAP的历史可能是在青少年和青年期IBS的风险增加。在有RAP病史的青少年和年轻人中，IBS症状可能与高水平的残疾和卫生服务使用相关。（J Pediatr 1998;132：1010-5）
ObjectivesTo assess symptoms of irritable bowel syndrome (IBS) in patients with recurrent abdominal pain (RAP) 5 years after their initial evaluation, to identify the relation of IBS symptoms to functional disability and health service use, and to determine the extent to which IBS symptoms are associated with life stress and poor psychosocial adjustment.MethodsPatients with RAP (n = 76) and control subjects (n = 49) completed a telephone interview; measures included the Bowel Disease Questionnaire, the Functional Disability Inventory, the Life Events Questionnaire, the Family Inventory of Life Events, the Center for Epidemiological Studies Depression Scale, the Self-Perception Profile for Adolescents, and the Health Resources Inventory.ResultsFive years after the initial evaluation, patients with RAP reported significantly more episodes of abdominal pain than did control subjects, as well as significantly higher levels of functional disability, school absence, and clinic visits for abdominal distress. Female patients with RAP were more likely than female control subjects to meet the Manning criteria for IBS. Among patients with RAP, higher levels of IBS symptoms were associated with significantly greater functional disability, more clinic visits, more life stress, higher levels of depression, and lower academic and social competence.ConclusionFemale patients with a history of RAP may be at increased risk of IBS during adolescence and young adulthood. Among adolescents and young adults with a history of RAP, IBS symptoms are likely to be associated with high levels of disability and health service use. (J Pediatr 1998;132:1010-5)