CEREBROSPINAL-FLUID FLOW WAVE-FORMS - ANALYSIS IN PATIENTS WITH CHIARI-I MALFORMATION BY MEANS OF GATED PHASE-CONTRAST MR-IMAGING VELOCITY-MEASUREMENTS
CEREBROSPINAL-FLUID FLOW WAVE-FORMS - ANALYSIS IN PATIENTS WITH CHIARI-I MALFORMATION BY MEANS OF GATED PHASE-CONTRAST MR-IMAGING VELOCITY-MEASUREMENTS
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DOI：
10.1148/radiology.196.1.7784567
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发表时间：
1995-07-01
期刊：
影响因子：
19.7
通讯作者：
HEILMAN, CB
中科院分区：
文献类型：
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作者：
BHADELIA, RA;BOGDAN, AR;HEILMAN, CB
目的：探讨Chiari I畸形患者减压手术前后心动周期相关脑脊液(CSF)血流脉动的特点。材料与方法：对15例Chiari I畸形患者和23例健康人进行电影相位对比磁共振成像。10名患者在减压手术后也接受了检查。在上颈椎蛛网膜下腔和髓前池中选择四个感兴趣区。绘制心动周期波形的速度和分数，并评估幅度、时间和脑脊液位移参数。结果：在Chiari I组患者中，在枕大孔下方发现收缩和舒张期脑脊液血流搏动受损和无改变。手术后，枕大孔下方的收缩期血流搏动得到改善。结论：脑脊液血流波形分析有助于显示枕大孔区脑脊液血流的异常情况，并有助于了解Chiari I畸形患者减压术的益处。
PURPOSE: To determine the features of the cardiac cycle-related cerebrospinal fluid (CSF) flow pulsations in patients with Chiari I malformation before and after decompressive surgery.MATERIALS AND METHODS: Fifteen patients and 23 healthy subjects underwent cine phase-contrast magnetic resonance imaging. Ten patients were also examined after decompressive surgery. Four regions of interest were selected in the upper cervical subarachnoid space and premedullary cistern. Velocity and fraction of the cardiac cycle waveforms were plotted, and amplitude, temporal, and CSF displacement parameters were assessed.RESULTS: In the Chiari I patients, impaired systolic and unaltered diastolic CSF flow pulsations immediately below the foramen magnum were identified. After surgery, the systolic flow pulsations immediately below the foramen magnum improved. Good correlation with postsurgical improvement was observed.CONCLUSION: CSF flow waveform analysis helps demonstrate abnormalities in CSF flow at the foramen magnum and the benefits of decompressive surgery in patients with the Chiari I malformation.