Cholinesterases in the amyloid angiopathy of Alzheimer's disease.
Cholinesterases in the amyloid angiopathy of Alzheimer's disease.
复制标题
阿尔茨海默病淀粉样血管病中的胆碱酯酶。
DOI:
10.1002/ana.410310517
复制
发表时间:
1992
影响因子:
11.2
通讯作者:
Geula,C
中科院分区:
文献类型:
--
作者:
Mesulam,M;Carson,K;Price,B;Geula,C
Vessels affected by amyloid angiopathy in patients with Alzheimer's disease also displayed intense acetylcholinestearase and butyrylcholinesterase activity when examined by light and electron microscopy. The enzymatic properties of the vessel‐bound cholinesterases were identical to those of the cholinesterases associated with senile plaques and neurofibrillary tangles. This cholinesterase activity is of unknown origin but represents one of the very few features common to all the major pathological markers of Alzheimer's disease.