High-Photoluminescence-Yield Gold Nanocubes: For Cell Imaging and Photothermal Therapy
High-Photoluminescence-Yield Gold Nanocubes: For Cell Imaging and Photothermal Therapy
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DOI：
10.1021/nn901064m
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发表时间：
2010-01-01
期刊：
影响因子：
17.1
通讯作者：
Chen, Jiyao
中科院分区：
文献类型：
--
作者：
Wu, Xi;Ming, Tian;Chen, Jiyao
金纳米立方体表现出独特的光学性质，具有高的光致发光量子产率和显著增强的544 nm消光带。4×10~(-2)的荧光产额约为金纳米棒的200倍，这使得金纳米立方体可以用普通的单光子激发方法成功地用于人肝癌细胞(QGY)和人胚胎肾细胞(293T)的细胞成像。金纳米立方体的高消光系数也有利于它们对QGY和293T细胞进行光热治疗，表现出与金纳米棒相似的光杀灭效率。
Gold nanocubes demonstrate unique optical properties of the high photoluminescence (PL) quantum yield and a remarkably enhanced extinction band at 544 nm. The 4 X 10(-2) PL yield, which is about 200 times higher than that of gold nanorods, allows gold nanocubes to be successfully used in cell imaging of human liver cancer cells (QGY) and human embryo kidney cells (293T) with a common method of single-photon excitation. The high extinction coefficients of gold nanocubes also facilitate them carrying out the photothermal therapy of QGY and 293T cells, showing similar photokilling efficiency as compared to gold nanorods.