The pathogenesis of vesicular stomatitis virus, serotype Indiana, in Aedes aegypti mosquitoes. I. Intrathoracic injection.
The pathogenesis of vesicular stomatitis virus, serotype Indiana, in Aedes aegypti mosquitoes. I. Intrathoracic injection.
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水泡性口炎病毒（印第安纳血清型）在埃及伊蚊中的发病机制。
DOI：
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发表时间：
1976
影响因子：
3.3
通讯作者：
Y. Zee
中科院分区：
文献类型：
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作者：
I. Liu;Y. Zee
胸内注射后感染性病毒颗粒的分析表明，埃及伊蚊组织能够支持印第安纳血清型水泡性口炎病毒（VSV）的生长。尽管所有检测的组织（唾液腺、中肠、憩室、马氏小管和卵巢）都能够支持 VSV 生长，但唾液腺是唯一能够在感染后 9 天以上维持大量病毒的器官。对受感染组织的电子显微镜研究显示，病毒颗粒始终存在于所有器官的细胞质内，没有细胞核受累的证据。证明了唾液腺组织根尖腔中 VSV 晶体形成的直接证据。
Analysis of infectious virus particles after intrathoracic injection revealed that Aedes aegypti mosquito tissues are capable of supporting the growth of vesicular stomatitis virus (VSV), serotype Indiana. Although all tissues assayed (salivary gland, midgut, diverticulum, malphigian tubules, and ovary) were capable of supporting VSV growth, the salivary gland was the only organ capable of maintaining an appreciable amount of virus for periods longer than 9 days postinfection. Electron microscopic studies of infected tissues showed virus particles consistently within the cell cytoplasm of all organs with no evidence of nuclear involvement. Direct evidence of crystalline formation of VSV in the apical cavities of salivary gland tissue was demonstrated.