Genomic and phylogenetic perspectives on the evolution of prokaryotes
Genomic and phylogenetic perspectives on the evolution of prokaryotes
复制标题
原核生物进化的基因组学和系统发生学视角
DOI：
10.1080/10635150117729
复制
发表时间：
2001-08-01
影响因子：
6.5
通讯作者：
Brown, JR
中科院分区：
文献类型：
--
作者：
Brown, JR
原核生物一直处于基因组测序革命的最前沿。许多基因组已经完全测序，揭示了细菌和古细菌基因组的内容和组织。然而，原核生物的一个有意义的进化图景仍然远离我们。大部分问题在于理解基因组进化的模式和克里思。在这里，苯丙氨酰-tRNA合成酶被用作在一些原核基因的进化中横向基因转移、操纵子重组和基因募集之间复杂相互作用的例子。有前途的新方法，基因组分析，这可能会增加我们的理解原核生物的进化，并帮助他们的分类，进行了讨论。
Prokaryotes have been at the forefront of the genome sequencing revolution. Many genomes have been completely sequenced, revealing much about bacterial and archaeal genome content and organization. Yet, a meaningful evolutionary picture of prokaryotes still eludes us. Much of the problem lies in understanding the mode and tempo of genome evolution. Here phenylalanyl-tRNA synthetase is used as an example of the complex interplay among lateral gene transfer, operon recombination, and gene recruitment in the evolution of some prokaryotic genes. Promising new approaches to genomic analyses, which could add to our understanding prokaryotic evolution and help in their classification, are discussed.