Regioselective glycosylation: synthesis of alpha-indoline nucleosides.
Regioselective glycosylation: synthesis of alpha-indoline nucleosides.
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区域选择性糖基化：α-二氢吲哚核苷的合成。
DOI：
10.1081/ncn-200067398
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发表时间：
2005
期刊：
影响因子：
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通讯作者：
Valente,EdwardJ
中科院分区：
文献类型：
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作者：
Brown,KennethL;Chandra,Tilak;Zou,Shawn;Valente,EdwardJ
Novel indoline ribonucleosides with theα-N-glycoside configuration are synthesized with very high regioselectivity in 90–96% yield, using TMS protected indolines and 2,3-O-(1-methylethylidene)-5-O-(triphenylmethyl)-α/β-d-ribofuranose. The structures of these ribonucleosides were elucidated with X-ray crystallography as well as 2D (NOESY, COSY, and HMQC) NMR spectroscopy.
