Lower extremity peripheral arterial disease in hospitalized patients with coronary artery disease
Lower extremity peripheral arterial disease in hospitalized patients with coronary artery disease
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DOI：
10.1191/1358863x03vm506ra
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发表时间：
2003-01-01
影响因子：
3.5
通讯作者：
McBride, PE
中科院分区：
文献类型：
--
作者：
Dieter, RS;Tomasson, J;McBride, PE
冠状动脉疾病（CAD）在外周动脉疾病（PAD）患者中的患病率已得到很好的定义。然而，PAD在住院CAD患者中的患病率尚未确定。踝臂指数（ABI）是一种有用的无创性工具，以筛选PAD。本研究的目的是通过测量ABI评估住院CAD患者PAD的患病率。这项研究是在威斯康星州大学医院和诊所住院心血管医学服务进行的。病情稳定的CAD患者在出院前被邀请参加研究。收集有关心血管危险因素、既往PAD病史、体格检查和ABI的数据。ABI小于或等于0.9或既往下肢血管再生史被认为是显著PAD的指征。共招募了100名患者（66名男性和34名女性）。发现40例患者患有PAD（非血管重建PAD患者的平均ABI = 0.67）。通过测量ABI，37例（25例男性）PAD阳性，3例既往血运重建后ABI得到纠正。在这些患者中，21例（52.5%）既往记录有PAD。PAD患者年龄较大（p = 0.003），吸烟史较多（p = 0.002），更可能患有糖尿病（p = 0.012）、高血压（p = 0.013）和血脂异常（p = 0.055）。总之，住院的CAD患者可能合并PAD。该患者人群中PAD的风险因素包括高龄、吸烟史、糖尿病、高血压、血脂异常和脉搏检查异常。通过测量踝臂指数很容易识别PAD患者。
The prevalence of coronary artery disease ( CAD) in patients with peripheral arterial disease ( PAD) has been well defined. However, the prevalence of PAD in hospitalized patients with CAD has not been defined. The ankle - brachial index (ABI) is a useful non-invasive tool to screen for PAD. The aim of our study was to assess the prevalence of PAD in hospitalized patients with CAD by measuring the ABI. The study was conducted at the University of Wisconsin Hospital and Clinics inpatient Cardiovascular Medicine Service. Medically stable patients with CAD were invited to participate prior to hospital discharge. Data regarding cardiovascular risk factors, history of previous PAD, physical examination, and ABI were collected. An ABI less than or equal to 0.9 or a history of previous lower extremity vascular invention was considered to be indicative of significant PAD. A total of 100 patients ( 66 men and 34 women) were recruited. Forty patients were found to have PAD ( mean ABI in non-revascularized patients with PAD = 0.67). By measuring the ABI, 37 ( 25 men) were positive for PAD and three had an ABI corrected with previous revascularization. Of these patients, 21 (52.5%) had previously documented PAD. Patients with PAD were older ( p = 0.003), had a greater smoking history ( p = 0.002), were more likely to have diabetes ( p = 0.012), hypertension ( p = 0.013) and a trend towards more dyslipidemia ( p = 0.055). In conclusion, hospitalized patients with CAD are likely to have concomitant PAD. Risk factors for PAD in this patient population include advanced age, history of smoking, diabetes, hypertension, dyslipidemia and abnormal pulse examination. Identification of patients with PAD by measuring the ankle brachial index is easily done.