Telephone Administration of the Mental Alternation Test: Sensitivity to Cognitive Decline and Practice Effects across Mid life and Late Life

Telephone Administration of the Mental Alternation Test: Sensitivity to Cognitive Decline and Practice Effects across Mid life and Late Life
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DOI:
10.1159/000321176
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发表时间:
2010-01-01
期刊:
影响因子:
5.7
通讯作者:
Tuokko, Holly
Tuokko, Holly
中科院分区:
医学3区
文献类型:
--
作者:
McComb, Erin;Brewster, Paul;Tuokko, Holly

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背景:我们评估了电话管理的心理选择测验(MAT,一种口述测验)对老年人认知功能的远程评估的效用。我们检查了(1)MAT分数对4个年龄组认知变化的敏感度,(2)与重复给药相关的练习效果,以及(3)不同年龄组练习效果的一致性。方法:随机抽取社区志愿者,分为青壮年(45~54岁,n=51)、中年(55~,n=58)、青壮年(65~74岁,n=43)和老年组(75~85岁,n=43)。参与者在两周内完成了两次垫子。数据分析采用混合方差分析。结果:我们发现年龄对垫子性能有影响[F(3191)=11.37;p<0.001],计划的比较显示,老年人的得分明显较低(p<0.05)。第二次MAT治疗的得分显著高于第一次治疗[F(1,191)=12.82;p<0.001],但这种练习效果在不同年龄组之间没有差异。结论:MAT对成年后认知功能减退很敏感。实践效果是可测量的,但在观察到的年龄队列中是一致的。作为一种简短的电话管理测试,MAT代表了一种很有希望的老年人认知功能测量方法,适用于大规模流行病学研究。版权所有(C)2010 S.Karger AG,巴塞尔
Background: We evaluated the utility of the telephone-administered Mental Alternation Test (MAT, an oral variant of the Trail-Making Test) for remote assessment of cognitive functioning in older adults. We examined (1) the sensitivity of MAT scores to cognitive change across 4 age groups, (2) practice effects associated with repeat administration, and (3) the uniformity of practice effects across age groups. Methods: Community-dwelling volunteers were recruited randomly and categorized as young-middle-aged (45-54 years; n = 51), middle-aged (55-64 years; n = 58), young-old (65-74 years; n = 43) or old-old (75-85 years; n = 43). The participants completed the MAT twice within 2 weeks. The data were analyzed using mixed ANOVA. Results: We found an effect of age on MAT performance [F(3, 191) = 11.37; p < 0.001], with planned comparisons revealing significantly lower scores in the old-old (p < 0.05). The scores on the second MAT administration were significantly higher than on the first administration [F(1, 191) = 12.82; p < 0.001], but this practice effect did not differ across age groups. Conclusions: The MAT was sensitive to cognitive decline in older adulthood. Practice effects were measurable but uniform across the observed age cohorts. As a brief telephone-administered test, the MAT represents a promising measure of cognitive functioning in older adults that is feasible for use in large-scale epidemiological studies. Copyright (C) 2010 S. Karger AG, Basel