Long-term follow-up of patients treated with a combination of continuous ambulatory peritoneal dialysis and hemodialysis.
Long-term follow-up of patients treated with a combination of continuous ambulatory peritoneal dialysis and hemodialysis.
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对连续门诊腹膜透析和血液透析联合治疗的患者进行长期随访。
DOI：
10.1177/089686080402400614
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发表时间：
2006
期刊：
影响因子：
--
通讯作者：
Hiromichi Suzuki
中科院分区：
文献类型：
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作者：
Hitoshi Hoshi;H. Nakamoto;Y. Kanno;H. Takane;Naofumi Ikeda;S. Sugahara;H. Okada;Hiromichi Suzuki
持续性非卧床腹膜透析（CAPD）和血液透析（HD）在治疗肾功能衰竭患者中各有优势。在CAPD中，溶质清除有时在具有相对较大的肌肉质量的患者中不足，从而产生高水平的肌酐。为了弥补这一不足，需要频繁交换和大量透析液。我们以前报道过，每周一次HD有助于溶质清除不足的CAPD患者。在本研究中，我们随访了9例CAPD患者，随访时间超过3年，这些患者接受了额外的每周HD。HD辅助治疗使受试者的每周腹膜肌酐清除率显著增加至45 +/- 3 L（平均值+/-标准差）;在研究过程中，这些值升高至60 L以上。我们的研究结果表明，联合使用CAPD和HD可改善透析不足的CAPD患者的溶质清除率。
Continuous ambulatory peritoneal dialysis (CAPD) and hemodialysis (HD) both have advantages in the treatment of patients with renal failure. In CAPD, solute removal is sometimes insufficient in patients who have a relatively large muscle mass that produces high levels of creatinine. To compensate for this deficiency, frequent exchanges and large dialysate volumes are required. We previously reported that once-weekly HD helps CAPD patients who experience insufficient solute removal. In the present study, we followed, for more than 3 years, 9 CAPD patients who underwent additional weekly HD. Add-on HD therapy significantly increased the subjects' weekly peritoneal creatinine clearance to 45 +/- 3 L (mean +/- standard deviation); these values rose to more than 60 L over the course of the study. Our findings suggest that the combined use of CAPD and HD improves solute clearance in CAPD patients who are insufficiently dialyzed.