Long-term prognosis of laparoscopic gastrectomy for patients on antithrombotic therapy: a retrospective cohort study.
Long-term prognosis of laparoscopic gastrectomy for patients on antithrombotic therapy: a retrospective cohort study.
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接受抗血栓治疗的腹腔镜胃切除术患者的长期预后：一项回顾性队列研究。
DOI：
10.1007/s00595-022-02479-7
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Watanabe Y.
中科院分区：
文献类型：
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作者：
Yoshida M;Egi H＊;Ishimaru K;Koga S;Akita S;Kikuchi S;Sugishita H;Kuwabara J;Ogi Y;Matsui S;Watanabe Y.
目的胃切除术与抗血栓治疗的相互作用，特别是对远期预后的影响，目前尚未见报道。我们的目的是澄清短期和长期预后的胃切除术患者的抗血栓治疗。MethodsWe回顾了围手术期的数据和生存率的患者进行腹腔镜远端胃切除术（LDG）在我院2010年至2013年。结果有119例患者参加了这项回顾性研究：31例患者正在服用抗血栓药物（抗血栓治疗组），88例患者未服用抗血栓药物（非抗血栓治疗组）。ATT组的平均年龄显著高于非ATT组。两组间术中出血量或术后血红蛋白水平无显著差异。ATT组仅1例患者发生出血并发症，两组的术后并发症发生率相当。在随访期间，ATT组19.4%的患者和非ATT组4.5%的患者发生了脑血管或心血管事件;然而，两组之间的5年总生存率没有显著差异结论抗栓治疗不影响LDG后患者的近期或远期预后。
PurposeFew studies have reported on the interactions between gastrectomy and antithrombotic therapy, especially the long-term prognosis. We aimed to clarify the short- and long-term prognosis of gastrectomy for patients on antithrombotic therapy.MethodsWe reviewed the perioperative data and survival rate of patients who underwent laparoscopic distal gastrectomy (LDG) at our institute between 2010 and 2013.ResultsThere were 119 patients enrolled in this retrospective study: 31 who were taking antithrombotic drugs (antithrombotic therapy (ATT) group), and 88 who were not (non-ATT group). The mean age was significantly higher in the ATT group than in the non-ATT group. No significant differences were observed in the amount of intraoperative bleeding or blood hemoglobin level after surgery between the groups. Bleeding complications occurred in only one patient from the ATT group, and the postoperative complication rate was comparable between the groups. During follow-up, cerebrovascular or cardiovascular events developed in 19.4% of the ATT group patients and 4.5% of the non-ATT group patients; however, there were no significant differences in the 5-year overall survival rates between the groups (ATT group, 76.9%; non-ATT group, 82.9%).ConclusionsAntithrombotic therapy did not affect the short-term or long-term prognosis of patients after LDG.