Rapid feature selective neuronal synchronization through correlated latency shifting
Rapid feature selective neuronal synchronization through correlated latency shifting
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DOI：
10.1038/84032
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发表时间：
2001-02-01
影响因子：
25
通讯作者：
Singer, W
中科院分区：
文献类型：
--
作者：
Fries, P;Neuenschwander, S;Singer, W
自发的大脑活动可能会影响处理，如果它是结构化的。我们发现猫初级视觉皮层的神经元对在反应潜伏期中表现出相关的波动，特别是当它们有重叠的感受野或相似的取向偏好时。相关性发生在半球内部和半球之间，但只有当局部场电位（LFPs）在伽马频率范围（40-70 Hz）振荡时才会发生。在这个范围内，反应开始前的LFP波动预测了反应延迟；阴性（阳性）lfp与早期（晚期）反应相关。低于10 Hz的振荡引起响应幅度的协变，但对延迟没有柱状选择性或协调效应。因此，在高伽马活动期间，自发活动表现出明显的柱特异性相关模式。因此，皮层细胞在兴奋性上经历了连贯的波动，从而增强了对空间连续或方向相似的轮廓的反应的时间一致性。由于同步反应比分散反应更有可能经历快速和联合的加工，自发活动可能在早期视觉过程中很重要。
Spontaneous brain activity could affect processing if it were structured,. We show that neuron pairs in cat primary visual cortex exhibited correlated fluctuations in response latency, particularly when they had overlapping receptive fields or similar orientation preferences. Correlations occurred within and across hemispheres, but only when local field potentials (LFPs) oscillated in the gamma-frequency range (40-70 Hz). In this range, LFP fluctuations preceding response onset predicted response latencies; negative (positive) LFPs were associated with early (late) responses. Oscillations below 10 Hz caused covariations in response amplitude, but exhibited no columnar selectivity or coordinating effect on latencies. Thus, during high gamma activity, spontaneous activity exhibits distinct, column-specific correlation patterns. Consequently, cortical cells undergo coherent fluctuations in excitability that enhance temporal coherence of responses to contours that are spatially contiguous or have similar orientation. Because synchronized responses are more likely than dispersed responses to undergo rapid and joint processing, spontaneous activity may be important in early visual processes.