Suicide by Multidrug Ingestion: Hypothesis on the Role Played by the Self-Administration of Activated Charcoal
Suicide by Multidrug Ingestion: Hypothesis on the Role Played by the Self-Administration of Activated Charcoal
复制标题
摄入多种药物自杀：关于活性炭自我给药作用的假设
DOI：
10.1097/01.paf.0000257424.07395.b0
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发表时间：
2007
影响因子：
1
通讯作者：
N. De Giovanni
中科院分区：
文献类型：
--
作者：
D R. Vantaggiato;N. De Giovanni
据报道，一起致命的自杀性药物摄入，以及活性炭。死亡发生在自我给药后31小时。尸检发现大量胃内容物，似乎是一个黑色的致密块。毒理学分析表明，存在毒性水平的去烷基泮和曲唑酮;安乃近和普地诺也被检测到。所获得的结果支持了由于活性炭的自我给药延迟急性中毒死亡的假设，其消除可能受到普利地诺的作用的阻碍。
A fatal suicidal ingestion of drugs, together with activated charcoal, is reported. The death occurred 31 hours after the self-administration. The autopsy revealed a large amount of gastric content that appeared to be a compact mass of black color. Toxicologic analyses showed the presence of toxic levels of desalkylflurazepam and trazodone; metamizole and pridinol were also detected. The obtained results supported the hypothesis of a death due to acute intoxication delayed by the self-administration of activated charcoal, which elimination was probably hindered by the action of pridinol.