Breed incidence of lymphoma in a UK population of insured dogs.
Breed incidence of lymphoma in a UK population of insured dogs.
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DOI：
10.1111/j.1476-5810.2003.00025.x
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发表时间：
2003-12-01
影响因子：
2.1
通讯作者：
Wood, J L N
中科院分区：
文献类型：
--
作者：
Edwards, D S;Henley, W E;Wood, J L N
犬淋巴瘤是犬自发性肿瘤最常见的形式之一。对犬淋巴瘤的遗传和环境风险因素的进一步了解，包括品种差异，可能对人类非霍奇金淋巴瘤的研究有相对的好处。在这项研究中，从宠物保险公司的数据被用来估计发病率犬淋巴瘤的血统在英国的品种。在总共130，684只被保险的狗中，有103只被诊断为淋巴瘤。一个显着的品种效应被发现与拳击手，斗牛犬和斗牛獒品种，都有很高的发病率淋巴瘤。记录的淋巴瘤病例数量较少，可能限制了我们检测其他风险升高的品种的能力。淋巴瘤的发病率随着年龄的增长而增加，在10岁时达到高峰。
Canine lymphoma is one of the commonest forms of spontaneous canine neoplasia. Improved understanding of the genetic and environmental risk factors for canine lymphoma, including breed differences, may have comparative benefits for the study of non-Hodgkin's lymphoma in humans. In this study, data from a pet insurance company were used to estimate the incidences of canine lymphoma for pedigree breeds in the UK. Out of a total of 130,684 insured dogs, 103 had a diagnosis of lymphoma recorded. A significant breed effect was found with the boxer, bulldog and bull mastiff breeds, all having a high incidence of lymphoma. The small number of lymphoma cases recorded may have limited our ability to detect other breeds with an elevated risk. Incidence of lymphoma was found to increase with age, peaking at 10 years of age.