Discrimination, Racial Identity, and Cytokine Levels Among African-American Adolescents
Discrimination, Racial Identity, and Cytokine Levels Among African-American Adolescents
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DOI：
10.1016/j.jadohealth.2015.01.017
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发表时间：
2015-05-01
影响因子：
7.6
通讯作者：
Chen, Edith
中科院分区：
文献类型：
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作者：
Brody, Gene H.;Yu, Tianyi;Chen, Edith
目的：低度炎症是几种慢性老年性疾病的致病机制，由循环细胞因子水平来衡量。确定与非裔美国年轻人的炎症相关的因素可能会对健康方面种族差异的潜在机制有深入的了解。这项研究的目的是确定(1)17-19岁报告的种族歧视是否预示着22岁时细胞因子水平的升高，以及(2)这种联系在具有积极种族认同的年轻人中较低。方法：采用纵向研究设计，以160名17岁的非裔美国人为社区样本。采用问卷调查法测量患者的辨别力和种族认同感，并抽血检测基础细胞因子水平。结果：在控制了社会经济风险、生活压力、抑郁症状和体重指数后，种族歧视(beta=.307；p
Purpose: Low-grade inflammation, measured by circulating levels of cytokines, is a pathogenic mechanism for several chronic diseases of aging. Identifying factors related to inflammation among African-American youths may yield insights into mechanisms underlying racial disparities in health. The purpose of the study was to determine whether (1) reported racial discrimination from ages 17-19 years forecasts heightened cytokine levels at the age of 22 years and (2) this association is lower for youths with positive racial identities.Methods: A longitudinal research design was used with a community sample of 160 African-Americans who were aged 17 years at the beginning of the study. Discrimination and racial identity were measured with questionnaires, and blood was drawn to measure basal cytokine levels. Ordinary least squares regression analyses were used to examine the hypotheses.Results: After controlling for socioeconomic risk, life stress, depressive symptoms, and body mass index, racial discrimination (beta = .307; p