The desert wormwood (Artemisia herba-alba) - From Arabian folk medicine to a source of green and effective nanoinsecticides against mosquito vectors
The desert wormwood (Artemisia herba-alba) - From Arabian folk medicine to a source of green and effective nanoinsecticides against mosquito vectors
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DOI：
10.1016/j.jphotobiol.2018.02.012
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发表时间：
2018-03-01
影响因子：
5.4
通讯作者：
Benelli, Giovanni
中科院分区：
文献类型：
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作者：
Aziz, Al Thabiani;Alshehri, Mohammed Ali;Benelli, Giovanni
开发生态友好和有效的杀虫剂对全世界的公共卫生至关重要。在这里，我们专注于沙漠艾草（蒿属植物），广泛用于阿拉伯传统医学，作为一种来源的绿色纳米杀虫剂对蚊子的载体，以及生长抑制剂，用于对微生物病原体。用A.在印度和沙特阿拉伯按蚊、伊蚊和库蚊品系上测试了草药-白蛋白提取物。对A.通过LC-DAD-MS和1H-1 NMR研究确定白花草提取物。然后，AgNPs进行了研究，使用紫外可见光谱，XRD，FTIR光谱，TEM，和EDX分析。蒿草-白合成的银纳米颗粒对来自印度和沙特阿拉伯菌株的蚊子表现出高的杀幼虫毒性。AgNPs对印度菌株的LC 50为9.76 μ g/ml。stephensi为10.70 μ g/ml。埃及伊蚊为11.43 μ g/ml。对沙乌地阿拉伯菌株的毒力为33.58 μ g/ml。埃及伊蚊为38.06 μ g/ml。pipiens。在杀成虫实验中，A.银合欢提取物显示LC 50范围为293.02 - 450 μ g/ml，而AgNP LC 50范围为8.22 - 27.39 μ g/ml。此外，低剂量的AgNP抑制了选定的微生物病原体的生长。总体而言，A.银合欢可以进一步被认为是植物化学物质（特别是皂苷）的来源，用于有效和迅速地制备具有针对高度公共卫生重要性的物种的相关杀虫和杀菌活性的AgNP。
The development of eco-friendly and effective insecticides is crucial for public health worldwide. Herein, we focused on the desert wormwood (Artemisia herba-alba), a plant widely used in Arabian traditional medicine, as a source of green nanoinsecticides against mosquito vectors, as well as growth inhibitors to be employed against microbial pathogens. Ag nanoparticles (AgNPs) fabricated with the A. herba-albs extract were tested on Indian and Saudi Arabian strains of Anopheles, Aedes and Culex mosquitoes. The chemical profile of the A. herba-alba extract was determined by LC-DAD-MS and H-1 NMR studies. Then, AgNPs were studied using UV-vis spectroscopy, XRD, FTIR spectroscopy, TEM, and EDX analyses. Artemisia herba-alba-synthesized AgNPs showed high larvicidal toxicity against mosquitoes from both Indian and Saudi Arabian strains. LC50 of AgNPs against Indian strains was 9.76 mu g/ml for An. stephensi, 10.70 mu g/ml for Ae. aegypti and 11.43 mu g/ml for Cx. quinquefasciatus, whereas against Saudi Arabian strains it was 33.58 mu g/ml for Ae. aegypti and 38.06 mu g/ml for Cx. pipiens. In adulticidal experiments, A. herba-alba extract showed LC50 ranging from 293.02 to 450 mu g/ml, while AgNP LC50 ranged from 8.22 to 27.39 mu g/ml. Further, low doses of the AgNPs inhibited the growth of selected microbial pathogens. Overall, A. herba-alba can be further considered as a source of phytochemicals, with special reference to saponins, for effective and prompt fabrication of AgNPs with relevant insecticidal and bactericidal activity against species of high public health importance.