Ocular Myasthenia
Ocular Myasthenia
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DOI:
10.1016/j.ncl.2018.01.003
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发表时间:
2018-05-01
影响因子:
2.4
通讯作者:
Kaminski, Henry J.
中科院分区:
文献类型:
--
作者:
Al-Haidar, Mohammed;Benatar, Michael;Kaminski, Henry J.
Ocular myasthenia is a form of myasthenia gravis in which weakness is restricted to the ocular muscles and may produce significant visual disability. Patients present with fluctuating ptosis, diplopia, or a combination of both. Examination may show any type of ocular motility deficit ranging from isolated muscle palsy to complete ophthalmoplegia. Co-gan lid twitch, enhanced ptosis, peek sign, and saccadic fatigue are specific examination findings that support the clinical diagnosis of myasthenia gravis. Confirmation of the diagnosis is challenging with autoantibody serology, and repetitive nerve stimulation studies are often negative.