Sidestream Dark Field (SDF) imaging: a novel stroboscopic LED ring-based imaging modality for clinical assessment of the microcirculation
Sidestream Dark Field (SDF) imaging: a novel stroboscopic LED ring-based imaging modality for clinical assessment of the microcirculation
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DOI：
10.1364/oe.15.015101
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发表时间：
2007-11-12
期刊：
影响因子：
3.8
通讯作者：
Ince, C.
中科院分区：
文献类型：
--
作者：
Goedhart, P. T.;Khalilzada, M.;Ince, C.
侧流暗场 (SDF) 成像是一种基于 LED 环的频闪成像模式，用于微循环的临床观察。 SDF 成像通过与正交偏振光谱成像的比较得到验证。使用两种技术测量甲襞毛细血管直径和红细胞速度，并获得相同的定量结果。开发了一种图像质量系统，用于定量比较使用 OPS 和 SDF 成像舌下获取的微循环图像的质量。 OPS 和 SDF 成像的小静脉对比度、清晰度和质量相当。然而，使用 SDF 成像显示毛细血管对比度和质量明显更高。此外，使用 SDF 成像可以更清楚地观察到静脉颗粒度。 (c) 2007 年美国光学学会
Sidestream Dark Field (SDF) imaging, a stroboscopic LED ring-based imaging modality, is introduced for clinical observation of the microcirculation. SDF imaging is validated by comparison to Orthogonal Polarization Spectral imaging. Nailfold capillary diameters and red blood cell velocities were measured using both techniques and equal quantitative results were obtained. An image quality system was developed to quantitatively compare the quality of sublingually-acquired microcirculatory images using OPS and SDF imaging. Venular contrast, sharpness, and quality were shown to be comparable for OPS and SDF imaging. However, capillary contrast and quality were shown to be significantly higher using SDF imaging. Venular granularity, in addition, was more clearly observable using SDF imaging. (c) 2007 Optical Society of America