Body mass index and incidence of dementia -: The PAQUID study

Body mass index and incidence of dementia -: The PAQUID study
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DOI:
10.1212/01.wnl.0000038910.46217.aa
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发表时间:
2003-01-14
期刊:
影响因子:
9.9
通讯作者:
Barberger-Gateau, P
Barberger-Gateau, P
中科院分区:
医学1区
文献类型:
--
作者:
Nourhashémi, F;Deschamps, V;Barberger-Gateau, P

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To study the relationship between body mass index (BMI) and risk of dementia, a cohort of 3,646 individuals aged :65 years living at home and without cognitive disorders at baseline were followed up for 8 years (the PAQUID [Personnes Agees Quid] Study). Subjects with a BMI < 21 had an increased risk of developing dementia as compared with subjects whose BMI was between 23 and 26 (odds ratio = 1.48, 95% CI = 1.08 to 2.04). However, when individuals who developed dementia early during the follow-up were excluded from the analysis, this relationship was no longer significant. A low BMI does not in itself seem to be a risk factor for dementia.