Withholding research results in academic life science. Evidence from a national survey of faculty.
Withholding research results in academic life science. Evidence from a national survey of faculty.
复制标题
DOI：
10.1001/jama.1997.03540390054035
复制
发表时间：
1997-04
期刊：
影响因子：
--
通讯作者：
D. Blumenthal;E. Campbell;Melissa S. Anderson;N. Causino;K. Louis
中科院分区：
文献类型：
--
作者：
D. Blumenthal;E. Campbell;Melissa S. Anderson;N. Causino;K. Louis
为了确定学术生命科学家中数据保留行为的普遍性和决定因素。设计邮寄调查的3394生命科学教师在50所大学，收到最多的资金从美国国立卫生研究院在1993年。参与者共有2167名教师回答了调查，回答率为64%。观察指标被调查者是否延迟发表研究成果超过6个月，以及被调查者是否在最近3年内拒绝与其他大学科学家分享研究成果。共有410名受访者（19.8%）报告称，在过去3年中，他们的研究成果至少有一次被推迟了6个月以上，以便申请专利，保护他们的科学领先地位，减缓不受欢迎的结果的传播，以便有时间进行专利谈判或解决知识产权所有权纠纷。此外，181名受访者（8.9%）表示在过去3年中拒绝与其他大学科学家分享研究成果。在多变量分析中，参与学术-产业研究关系和参与大学研究的商业化与出版延迟显著相关。比值比（OR）和95%置信区间（CI）分别为1.34（1.07-1.59）和3.15（2.88-3.41）。与拒绝分享结果相关的变量包括进行类似于人类基因组计划的研究（OR，2.09; 95%CI，1.75-2.42）、发表率（OR，1.02; 95%CI，1.01-1.03）和参与研究的商业化（OR，2.45; 95%CI，2.08-2.82）。结论：在生命科学研究者中，隐瞒研究结果并不是一个普遍的现象。然而，在最具生产力和创业精神的教师中，隐瞒更为常见。这些结果还表明，数据扣留影响了大量的生命科学教师和数据扣留的做法，建议进一步研究。
OBJECTIVES To identify the prevalence and determinants of data-withholding behaviors among academic life scientists. DESIGN Mailed survey of 3394 life science faculty in the 50 universities that received the most funding from the National Institutes of Health in 1993. PARTICIPANTS A total of 2167 faculty responded to the survey, a 64% response rate. OUTCOME MEASURES Whether respondents delayed publication of their research results for more than 6 months and whether respondents refused to share research results with other university scientists in the last 3 years. RESULTS A total of 410 respondents (19.8%) reported that publication of their research results had been delayed by more than 6 months at least once in the last 3 years to allow for patent application, to protect their scientific lead, to slow the dissemination of undesired results, to allow time to negotiate a patent, or to resolve disputes over the ownership of intellectual property. Also, 181 respondents (8.9%) reported refusing to share research results with other university scientists in the last 3 years. In multivariate analysis, participation in an academic-industry research relationship and engagement in the commercialization of university research were significantly associated with delays in publication. Odds ratios (ORs) and 95% confidence intervals (CIs) were 1.34 (1.07-1.59) and 3.15 (2.88-3.41), respectively. Variables associated with refusing to share results were conducting research similar to the Human Genome Project (OR, 2.09; 95% CI, 1.75-2.42), publication rate (OR, 1.02; 95% CI, 1.01-1.03), and engagement in commercialization of research (OR, 2.45; 95% CI, 2.08-2.82). CONCLUSIONS Withholding of research results is not a widespread phenomenon among life-science researchers. However, withholding is more common among the most productive and entrepreneurial faculty. These results also suggest that data withholding has affected a significant number of life-science faculty and further study on data-withholding practices is suggested.