Psychometric comparison of the Calgary Depression Scale for Schizophrenia and the Hamilton Depression Rating Scale

Psychometric comparison of the Calgary Depression Scale for Schizophrenia and the Hamilton Depression Rating Scale
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DOI:
10.1016/0920-9964(95)00070-4
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发表时间:
1996-05-01
影响因子:
4.5
通讯作者:
Atkinson, M
Atkinson, M
中科院分区:
医学2区
文献类型:
--
作者:
Addington, D;Addington, J;Atkinson, M

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这项研究比较了精神分裂症人群中抑郁的两种衡量标准。对112例住院精神分裂症患者进行汉密尔顿抑郁量表(HDRS)、卡尔加里抑郁量表(CDSS)和阳性与阴性症状量表(PANSS)评定。3个月后对89名患者进行了重新评估。对每个抑郁量表进行主成分因子分析。采用相关分析、因子分析和回归分析探讨抑郁测量与阳性症状和阴性症状的关系。CDSS总分与阳性症状和阴性症状均无显著相关性。HDRS总分与阳性症状和阴性症状均呈正相关,且多个因子与PANSS阳性分和阴性分显著相关。多元回归分析显示,HDRS对阳性症状分和阴性症状分的贡献率高于CDSS。CDSS与HDRS相比,因子较少,与阳性症状和阴性症状重叠较少。这表明,对于精神分裂症患者来说,它是一种比HDRS更具体的抑郁水平衡量标准。
This study compared two measures of depression in a population with schizophrenia. Inpatients (n=112) with schizophrenia, were assessed on the Hamilton (HDRS), and Calgary (CDSS) depression scales and the Positive and Negative Syndrome Scale (PANSS). Eighty-nine were reassessed 3 months later. A principal components factor analysis was applied to each depression scale. The relationship between measures of depression and positive and negative symptoms was explored using correlation, factor and regression analyses. There were no significant correlations between the total CDSS and positive or negative symptoms at either time. In contrast, the HDRS total score was correlated with both positive and negative syndromes at time 2. Moreover, a number of HDRS factors correlated significantly with the PANSS positive scale at both times and with the negative subscale score at time 2. Multiple regression analysis showed that the HDRS accounted for more of the variance in positive and negative symptoms scores than did the CDSS. The CDSS has fewer factors and less overlap with positive and negative symptoms than the HDRS. This suggests that it is a more specific measure of level of depression than the HDRS for individuals with schizophrenia.