Pyridine nucleotide oxidation‐reduction state of the cerebral cortex in the awake gerbil
Pyridine nucleotide oxidation‐reduction state of the cerebral cortex in the awake gerbil
复制标题
清醒沙鼠大脑皮层吡啶核苷酸氧化还原状态
DOI：
10.1002/jnr.490030508
复制
发表时间：
1978
影响因子：
4.2
通讯作者：
A. Mayevsky
中科院分区：
文献类型：
--
作者：
A. Mayevsky
本文介绍了一种研究清醒沙鼠脑缺血效应的新方法。来自皮质表面的NADH荧光的测量通过分时荧光计/反射计完成，该分时荧光计/反射计通过柔性光导和植入的套管连接到大脑。沙鼠脑缺氧和扩散性抑制的反应进行了描述。通过单侧闭塞颈动脉，在同侧半球测量NADH的增加。
A new approach to study the effect of ischemia on the brain of the awake gerbil is described. The measurement of NADH fluorescence from the surface of the cortex is done by a time‐sharing fluorometer/reflectometer connected to the brain via a flexible light guide and an implanted cannula. The response of the gerbil brain to anoxia and spreading depression is described. By unilateral occlusion of the carotid artery and increase in NADH was measured in the ipsilateral hemisphere.