Targeting a Low-Teen Intraocular Pressure by Trabeculectomy With a Fornix-based Conjunctival Flap: Continuous Japanese Case Series by a Single Surgeon
Targeting a Low-Teen Intraocular Pressure by Trabeculectomy With a Fornix-based Conjunctival Flap: Continuous Japanese Case Series by a Single Surgeon
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通过小梁切除术和基于穹窿的结膜瓣来降低青少年的低眼压：由一位外科医生进行的连续日本病例系列
DOI：
10.1097/ijg.0000000000000219
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发表时间：
2015
影响因子：
2
通讯作者：
H. Murata and M. Aihara
中科院分区：
文献类型：
--
作者：
Y. Aoyama;H. Murata and M. Aihara
目的：检查穹窿为基础的小梁切除术（TLE）由一个单一的外科医生进行的中期结果，并分析3个青光眼subtype.Methods的结果：连续前瞻性病例系列研究，以检查6个月的结果106眼[原发性开角型青光眼（OAG），剥脱性青光眼（XFG），炎性青光眼（ING）]，接受TLE与丝裂霉素C从2009年9月至2010年9月在东京大学医院。主要观察指标为TLE术后目标眼压（IOP）的存活率。根据青光眼亚型分析术后并发症和手术方式。结果：106眼TLE术后6个月，其中OAG 67眼，XFG 23眼，ING 16眼，眼压> 15 mm Hg者，眼压> 12 mm Hg者，眼压> 15 mm Hg者，眼压> 1 4只眼再次手术。在住院期间和住院后，3组中观察到的并发症相同，进行的手术相同。对于第一种定义，OAG、XFG和ING病例术后6个月的累积生存率分别为76.0%、73.9%和62.5%。对于第二种定义，OAG、XFG和ING病例的累积生存率分别为88.0%、78.3%和68.8%，respectively：由一名外科医生以穹窿为基础的结膜切口治疗TLE的6个月结果在3种类型的青光眼中没有差异。
Purpose:To examine the medium-term outcomes of fornix-based trabeculectomy (TLE) performed by a single surgeon and to analyze outcome in 3 glaucoma subtypes.Methods:Consecutive prospective case series study to examine the 6-month outcome of 106 eyes [primary open-angle glaucoma (OAG), exfoliation glaucoma (XFG), and inflammatory glaucoma (ING)] that underwent TLE with mitomycin C performed by a single surgeon from September 2009 to September 2010 at Tokyo University Hospital. Main outcome measure was survival rates of targeted intraocular pressure (IOP) after TLE. Postoperative complications and procedures were analyzed according to glaucoma subtypes. Life table analyses were then made according to 2 criteria of failure:(1) IOP was> 12 mm Hg with or without the use of topical glaucoma medications after 2 consecutive measurements or another surgery was needed; and (2) IOP was> 15 mm Hg.Results:A total of 106 eyes, which consisted of 67 OAG eyes, 23 XFG eyes, 16 ING eyes, were analyzed for 6 months after TLE. Four eyes were reoperated. During and after hospitalization, complications were equally observed and procedures were equally performed in all of the 3 groups. For the first definition, cumulative survival rates at 6 months after surgery in OAG, XFG, and ING cases were 76.0%, 73.9%, and 62.5%, respectively. For the second definition, cumulative survival rates in OAG, XFG, and ING cases were 88.0%, 78.3%, and 68.8%, respectively.Conclusions:Six-month outcome of TLE with a fornix-based conjunctival incision by a single surgeon that targeted an IOP< 12 mm Hg was not different among 3 types of glaucoma.