The Yeast Gene Order Browser: Combining curated homology and syntenic context reveals gene fate in polyploid species
The Yeast Gene Order Browser: Combining curated homology and syntenic context reveals gene fate in polyploid species
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DOI：
10.1101/gr.3672305
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发表时间：
2005-10-01
期刊：
影响因子：
7
通讯作者：
Wolfe, KH
中科院分区：
文献类型：
--
作者：
Byrne, KP;Wolfe, KH
我们开发了酵母基因序列浏览器(YGOB；http://wolfe.gen.tcd.ie/ygob)to)，便于可视化比较和计算分析酵母中的共线关系。YGOB上公布的数据目前涵盖7个物种，基于一组同源基因，这些同源基因已经根据序列相似性和基因组背景(同步性)进行了密集的人工整理。我们协调了不同实验室通过基因组复制形成的平行酿酒酵母基因对的列表，并给出了在酿酒酵母(551株，包括22株以前未鉴定的)、卡氏酵母(599株)和光滑假丝酵母(404株)中保留的几乎详尽的基因组对清单。
We developed the Yeast Gene Order Browser (YGOB; http://wolfe.gen.tcd.ie/ygob)to facilitate visual comparisons and computational analysis of synteny relationships in yeasts. The data presented in YGOB, currently covering seven species, are based on sets of homologous genes that have been intensively manually curated based on both sequence similarity and genomic context (synteny). We reconciled different laboratories' lists of paralogous Saccharomyces cerevisiae gene pairs formed by genome duplication (ohnologs), and present near-exhaustive lists of the ohnolog pairs retained in S. cerevisiae (551, including 22 previously unidentified), Saccharomyces castellii (599), and Candida glabrata (404).