Demographic differences in Down syndrome livebirths in the US from 1989 to 2006
Demographic differences in Down syndrome livebirths in the US from 1989 to 2006
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DOI：
10.1002/pd.2702
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发表时间：
2011-04-01
影响因子：
3
通讯作者：
Benn, Peter A.
中科院分区：
文献类型：
--
作者：
Egan, James F. X.;Smith, Kathleen;Benn, Peter A.
目的探讨美国唐氏综合征活产的人口统计学差异。方法利用1989年至2006年国家卫生统计中心（NCHS）出生证明数据，在纠正漏报后分析唐氏综合症的活产情况。我们根据母亲的年龄（15-34岁和35-49岁）创建了6个子集；美国地区，即东北、中西部、南部和西部；婚姻状况（已婚、未婚）；教育程度（= 13年）；种族（白人，黑人）；西班牙裔（非西班牙裔，西班牙裔）。假设出生证明报告没有变化，我们估计唐氏综合症的预期活产。实际出生的唐氏综合症的预期百分比是按年计算的。结果1989 ~ 2006年共分娩72 613 424例。预计有122519名唐氏综合症婴儿出生，实际有65492人出生。中西部地区的唐氏综合症活产率最高（67.6%）；西方最低（44.4%）。15 - 34岁的女性（61比43.8%）和15 - 34岁的女性的唐氏综合症活产率更高
Objective To explore demographic differences in Down syndrome livebirths in the United States.Methods Using National Center for Health Statistics (NCHS) birth certificate data from 1989 to 2006 we analyzed Down syndrome livebirths after correcting for under-reporting. We created six subsets based on maternal age (15-34 and 35-49 years old); US regions, that is, Northeast, Midwest, South and West; marital status, (married, unmarried); education, (= 13 years); race, (white, black); and Hispanic ethnicity, (non-Hispanic, Hispanic). We estimated expected Down syndrome livebirths assuming no change in birth certificate reporting. The percentage of expected Down syndrome livebirths actually born was calculated by year.Results There were 72 613 424 livebirths from 1989 to 2006. There were 122 519 Down syndrome livebirths expected and 65 492 were actually born. The Midwest had the most expected Down syndrome livebirths actually born (67.6%); the West was lowest (44.4%). More expected Down syndrome livebirths were born to women who were 15 to 34 years old (61 vs 43.8%) and to those with